Quantitative phase imaging for medical diagnosis

Quantitative Medical Imaging

The field of medical imaging is undergoing a radical shift, from subjective interpretation to quantitative analysis and measurement. This transformation is well established in the clinical trials arena, and is beginning to enter the diagnostic field as well. This paper will consider the implications of this change in terms of instrumentation, procedure, and analysis. It will include a brief rev...

Quantitative Phase Imaging

Coded aperture pair for quantitative phase imaging.

This Letter proposes a novel quantitative phase-imaging approach by optically encoding light fields into a complementary image pair followed by computational reconstruction. We demonstrate that the axial intensity derivative for phase recovery can be well estimated by a coded-aperture image pair without z axial scanning. The experimental results demonstrate that our approach can achieve higher ...

Quantitative Methods in Medical Imaging

Measurement and comparison of medical images is of growing importance for several reasons: (1) as medical imaging becomes ever more digital, and networks and archives of images proliferate, the opportunity will create the need; (2) automated approaches to treatment design (as in beam therapy), dose measurement (as when using monoclonal antibodies to deliver radiation), and surgery planning (e.g...

Quantitative Phase Shift Variance Imaging

Molecular ultrasound imaging is based on the detection of contrast agents (microbubbles) targeted to disease specific receptors in the vasculature. By quantifying the amount of the adherent microbubbles a change in the expression of these receptors and thus the disease development can be assessed. Quantification of microbubbles from ultrasound images in vivo was thus far mainly performed by ana...